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10/31/2017

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3/($6(-2,172'$2organs CardiacresponseatCR (8patientsevaluable) Renal response at CR (18evaluable) BMPC(%)(diagnosis)

MRD+(N=9) N(%) median(range) 5(72) 63(55Ͳ68)

MRDͲ (N=12) N(%) median(range) 4(44) 58(54Ͳ76)

0.156 0.269

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Results ‡ A further improvement of cardiac function compared to the time of CR attainment ‡ All 5 evaluable patients with MRDͲ; while Zero of 2 MRD + (P=0.047). ‡ Renal response ‡ 7 of 8 (87%) subjects with MRDͲ; while 4 of 8 (50%) with MRD+ (P=0.153). ‡ Overall, further improvement of cardiac or renal function after CR was significantly associated with absence of MRD (P=0.012).



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