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Single Superior Olivary Neurons Provide Divergent Inhibitory Input to Parallel Auditory Pathways in the Avian1 Brainstem...

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Single Superior Olivary Neurons Provide Divergent Inhibitory Input to Parallel Auditory Pathways in the Avian1 Brainstem R. Michael Burger, Karina S. Cramer, and Edwin W Rubel Virginia Merrill Bloedel Hearing Research Center and Dept. of Otolaryngology-HNS The University of Washington, Seattle, WA

Separate populations of SON neurons project to ipsilateral and contralateral targets

Mixed dye injections yield an average 65% double labeling.

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mixed dye Injection

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Abstract

Several Possible SON Output Patterns Schematic diagrams outlining three of the many possible output patterns of the SON. Populations of SON neurons are represented as individual somata with projections emanating from the SON at left.

NL

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ipsilateral SON

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A

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Uniform SON output:

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Panel A shows a single SON population projecting to all of its known brainstem targets as well as the higher order midbrain targets red lines.

decending pathway

to MLD, LLV

SON

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Table: Double labeling was rare in six cases where ipsilateral and contralateral targets were separetly injected. # of somata labeled from the contralateral SON and surrounding area(rhodamine column) and those labeled from ipsilateral targets (Alexa488 column) The very small proportion (